RESUMO
La infección por virus Chikungunya (CHIKV) presenta afectación articular en la mitad de las ocasiones. Esta afectación puede derivar en una artritis erosiva que, dada la elevada intervariabilidad en la presentación tanto clínica como serológica y el probable papel del condicionamiento genético en la gravedad y cronificación del cuadro, supone un gran reto diagnóstico y terapéutico. Existe una importante falta de evidencia científica que nos permita caracterizar la variabilidad del paciente y decidir el abordaje más adecuado
Chikungunya virus infection (CHIKV) is associated with joint involvement in half of the cases. This can lead to erosive arthritis which, given the high intervariability of clinical and serological presentations, and the probable role of genetic conditioning in the severity and chronification of the condition, represents a great diagnostic and therapeutic challenge. There is an important lack of scientific evidence that would enable us to characterize the variability of the patient and choose the most appropriate approach
Assuntos
Humanos , Feminino , Adulto , Febre de Chikungunya/complicações , Artrite/virologiaRESUMO
Chikungunya virus infection (CHIKV) is associated with joint involvement in half of the cases. This can lead to erosive arthritis which, given the high intervariability of clinical and serological presentations, and the probable role of genetic conditioning in the severity and chronification of the condition, represents a great diagnostic and therapeutic challenge. There is an important lack of scientific evidence that would enable us to characterize the variability of the patient and choose the most appropriate approach.
